When a handful of settlers survive an Apache attack on their wagon train they must put their lives into the hands of Comanche Todd, a white man who has lived with the Comanches most of his life and is wanted for the murder of three men.
There's a deficit of good, honest women in the West, and Roy Whitman wants to change that. His solution is to bring a caravan of over 100 mail-order brides from Chicago to California. It will be a long, difficult and dangerous journey for the women. So Whitman hires hardened, cynical Buck Wyatt to be their guide across the inhospitable frontier. But as disaster strikes on the trail, Buck just might discover that these women are stronger than he thinks.
Dan Evans, a small time farmer, is hired to escort Ben Wade, a dangerous outlaw, to Yuma. As Evans and Wade wait for the 3:10 train to Yuma, Wade's gang is racing to free him.
John Russell, disdained by his "respectable" fellow stagecoach passengers because he was raised by Indians, becomes their only hope for survival when they are set upon by outlaws.
Two tough Kentucky mountaineers join a trading expedition from St. Louis up the Missouri River to trade whisky for furs with the Blackfoot Indians. They soon discover that there is much more than the elements to contend with.
A trio of American adventurers marooned in rural Mexico are recruited by a beautiful woman to rescue her husband from Apaches.
A scout leading a wagon train through hostile Indian country gets involved with a Sioux chief's daughter.
Two young horse traders guide a Mormon wagon train to the San Juan Valley and encounter rugged terrain, the cutthroat Clegg gang, hospitable Navajo, and moral challenges on the journey.
One of the last bills signed by President Lincoln authorizes pushing the Union Pacific Railroad across the wilderness to California. But financial opportunist Asa Barrows hopes to profit from obstructing it. Chief troubleshooter Jeff Butler has his hands full fighting Barrows' agent, gambler Sid Campeau; Campeau's partner Dick Allen is Jeff's war buddy and rival suitor for engineer's daughter Molly Monahan. Who will survive the effort to push the railroad through at any cost?
Indian scout Tom Jeffords is sent out to stem the war between the American settlers and Apaches in the late 1870s Arizona. He learns that the Indians kill only to protect themselves, or out of retaliation for white atrocities.
Young scout Breck Coleman leads a wagon train along the dangerous trail to Oregon as he tries to get the affection of the beautiful pioneer Ruth Cameron and plans his revenge on the harsh scoundrels who murdered a friend of his in the past.
An authoritarian rancher rules an Arizona county with her private posse of hired guns. When a new Marshall arrives to set things straight, the cattle queen finds herself falling for the avowedly non-violent lawman. Both have itchy-fingered brothers, a female gunman enters the picture, and things go desperately wrong.
Two brothers discharged from the Confederate Army join a businessman for a cattle drive from Texas to Montana where they run into raiding Jayhawkers, angry Sioux, rough terrain and bad weather.
A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.
Brandon, a surveyor, dreams of building a railway to the west. He sets off with his son, Davy, to survey a route. They discover a new pass which will shave 200 miles off the expected distance, but they are set upon by a party of Cheyenne. One of them, a white renegade with only two fingers on his right hand, kills Brandon and scalps him. Davy is all alone now.
Jim Slater's father (whom he never knew) died in the Apache ambush at Gila Valley, and Jim is searching for the one survivor, who supposedly went for help but disappeared with a lot of gold. In the process, he gets several people gunning for him, and he keeps meeting liberated woman Karyl Orton, who may be on a similar mission. Renewed Apache hostilities and an impending range war provide complications.
Following the surrender of Geronimo, Massai, the last Apache warrior is captured and scheduled for transportation to a Florida reservation. On the way he manages to escape and heads for his homeland to win back his girl and settle down to grow crops. His pursuers have other ideas though.
Two Army officers, an alcoholic ex-Confederate soldier and a womanizing Mexican travel to Mexico on a secret mission to prevent a megalomaniacal ex-Confederate colonel from selling a cache of stolen rifles to a band of murderous Apaches.
A cattle-vs.-sheepman feud loses Connie Dickason her fiance, but gains her his ranch, which she determines to run alone in opposition to Frank Ivey, "boss" of the valley, whom her father Ben wanted her to marry. She hires recovering alcoholic Dave Nash as foreman and a crew of Ivey's enemies. Ivey fights back with violence and destruction, but Dave is determined to counter him legally... a feeling not shared by his associates. Connie's boast that, as a woman, she doesn't need guns proves justified, but plenty of gunplay results.
Four unwitting heroes cross paths on their journey to the sleepy town of Silverado. Little do they know the town where their family and friends reside has been taken over by a corrupt sheriff and a murderous posse. It's up to the sharp-shooting foursome to save the day, but first they have to break each other out of jail, and learn who their real friends are.
