The film takes place in one house, at an unspecified place, at an unspecified time. In this house, twelve dialogue stories take place and all have one thing in common - oppressive hopelessness. We witness everyday problems that become absurd under a distorted lens and become all the more real. The film follows with almost morbid interest the fates of people who, based on their actions and incompetence, are doomed. The question remains how far the characters from this "house" are.

The film tells futurist, architect, and inventor R. Buckminster Fuller's incredible story through two teens hoping to get laid, become punk gods, and survive high school.

A man in his mid-20s, still living at home with his mother and stepfather, puts all his eggs in one basket: the girl who works at his local coffee shop. The problem is, she has a serious boyfriend. As they become closer, the line between friendship and intimacy is blurred, and the situation forces both to examine where they are in their lives.

A teenager living with her sister and parents in Manhattan during the 1990s discovers that her father is having an affair.

A group of suburban teenagers try to support each other through the difficult task of becoming adults.

A 16-year-old girl takes her parents hostage after they miss her big jump-roping competition.

A young filmmaker in 1960s Paris juggles directing a cheesy sci-fi debacle, directing his own personal art film, coping with his crumbling relationship with his girlfriend, and a new-found infatuation with the sci-fi film's starlet.

When a self-destructive teenager is suspended from school and asked to look after his feisty alcoholic grandmother as a punishment, the crazy time they spend together turns his life around.

Leo and Angela Russo live a simple life in Queens, surrounded by their overbearing Italian-American family. When their son finds success on his high school basketball team, Leo tears the family apart trying to make it happen.

Eric returns home for a short visit and finds himself caught between reuniting with his sisters and chasing a victory with his old poker group. As the trip extends, Eric finds it increasingly difficult to avoid confrontations and revelations as his carefully constructed façade of his adulthood gives way to old childhood conflicts.

A nightmarish evening unfolds for neighbors David and Robert when they accidentally hit a woman on her bike and flee the scene. While David is increasingly plagued by feelings of guilt, Robert shows no remorse and becomes overbearing and possessive.

When motocross and heavy metal obsessed, 13-year-old Jacob's delinquent behavior forces CPS to place his little brother Wes with his aunt, Jacob and his emotionally absent father must finally take responsibility for their actions and each other in order to bring Wes home.

A two-bit promoter tries to take a women's wrestling team to the top.

A psychotic man opens fire in a diner, murdering numerous people before killing himself. The survivors struggle in different ways following this horrendous event: a doctor doubts his own instincts and elects to use an experimental medical procedure on his wife, while a gambler believes he's on a lucky streak. A waitress begins engaging in promiscuous sex, and a young girl whose father is among the dead gains unexpected fame.

In trouble with the local authorities, Mabel Simmons, notoriously known as Madea, is on the run from the law. With no place to turn, she moves in with her friend Bam who is recovering from surgery. Unbeknownst to Bam however, Madea is only using the "concerned friend" gag as a way to hide out from the police.

While doing the inventory for a lingerie outlet in a high rise office building, five attractive women are terrorized by a series of bizarre killings. They suspect that the strange janitor, who witnessed another series of killings six months previously, is at the bottom of the whole thing. Little do they know the real horror that they face in the end.

During the 1976 Soweto uprising, a white school teacher's life and values are threatened when he asks questions about the death of a young black boy who died in police custody.

A poor, struggling South Carolinian mother and daughter face painful choices with their resolve and pride. Bone, the eldest daughter, and Anney her tired mother, grow both closer and farther apart: Anney sees Glen as her last chance.

When a clumsy deadbeat accidentally kills his landlord, he must do everything in his power to hide the body, only to find that the distractions of lust, the death of his beloved brother, and a crew of misfit characters force him on a journey where a fortune awaits him.

The story of Bea Johnson from birth to graduation as she navigates life with an intellectually disabled parent and an extended family who can't quite agree on the best way to help.

An aspiring young filmmaker gets involved with an eccentric gangster for the financing of his first film.