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Host Neil deGrasse Tyson brings together celebrities, scientists and comedians to explore a variety of cosmic topics and collide pop culture with science in a way that late-night television has never seen before. Weekly topics range from popular science fiction, space travel, extraterrestrial life, the Big Bang, to the future of Earth and the environment. Tyson is an astrophysicist with a gifted ability to connect with everyone, inspiring us all to to "keep looking up."

Physicists Leonard and Sheldon find their nerd-centric social circle with pals Howard and Raj expanding when aspiring actress Penny moves in next door.

Beakman's World is an educational children's television show. The program is based on the Universal Press Syndicate syndicated comic strip You Can with Beakman and Jax created by Jok Church. The series premiered September 18, 1992 on The Learning Channel cable network and in national syndication. On September 18, 1993 it moved from national syndication to CBS Saturday morning children’s lineup. At the peak of its popularity, it was seen in nearly 90 countries around the world. The series was canceled in 1998. Reruns returned to national syndication in September 2006, after which it was transferred to local stations such as KICU. The show debuted a year prior to Bill Nye the Science Guy, which covered similar topics. The show's host, Paul Zaloom, still performs as Beakman in live appearances around the globe.

Based on Scott Aukerman’s popular podcast of the same name, COMEDY BANG! BANG! cleverly riffs on the well-known format of the late night talk show, infusing celebrity appearances and comedy sketches with a tinge of the surreal. In each episode, Aukerman engages his guests with unfiltered and improvisational lines of questioning, punctuated by banter and beats provided by bandleader, one-man musical mastermind Reggie Watts, to reinvent the traditional celebrity interview. Packed with character cameos, filmic shorts, sketches and games set amongst an off-beat world, COMEDY BANG! BANG! delivers thirty minutes of absurd laugh-loaded fun featuring some of the biggest names in comedy.

The outrageous comedy panel show hosted by the irrepressible Keith Lemon. Each episode sees top celebrities going head to head in a series of hilarious rounds unlike any other panel show.

Each week celebrity guests join Irish comedian Graham Norton to discuss what's being going on around the world that week. The guests poke fun and share their opinions on the main news stories. Graham is often joined by a band or artist to play the show out.

Stepping into the late-late slot vacated by David Letterman, Conan O'Brien stars in a show that far outdoes its competition in sheer strangeness. Along with the celebrity interviews and musical numbers typical of late-night talk shows, this program make frequent use of odd walk-on characters and frequent "visits" from celebrity guests.

Rob Dyrdek takes the funniest amateur internet videos and builds them into an episode of edgy, funny, and most importantly, timeless television.

The World's Fakest News Team tackle the biggest stories in news, politics and pop culture.

Each week, Jefferies tackles the week’s top stories from behind his desk and travels the globe to far-off locations to provide an eye opening look at hypocrisy around the world. Featuring interviews, international field pieces, and man on the ground investigations, Jim tackles the news of the day with no-bulls**t candor, piercing insight and a uniquely Aussie viewpoint.

Four teenage friends move from Minneapolis to Los Angeles to form a potential chart-topping boy band after Kendall is inadvertently discovered by an eccentric record executive, Gustavo Rocque. As they seize this opportunity of a lifetime, these friends embark on an exciting comedy and music-filled journey to prove to themselves and their record label that they are serious about their new career choice.

Host Adam Conover employs a combination of comedy, history and science to dispel widespread misconceptions about everything we take for granted.

Hilarious, totally-irreverent, near-slanderous political quiz show, based mainly on news stories from the last week or so, that leaves no party, personality or action unscathed in pursuit of laughs.

A comedic talk show from an alternate reality featuring unstable hosts, a variety of celebrities—both real and fake—and unusual studio action.

Jimmy Carr hosts proceedings as the 8 Out of 10 Cats crew take over the words and numbers quiz.

Trending news, pop culture, social media, original videos and more come together in host Joel McHale's weekly comedy commentary show.

Late Night with David Letterman is a nightly hour-long comedy talk show on NBC that was created and hosted by David Letterman. It premiered in 1982 as the first incarnation of the Late Night franchise and went off the air in 1993, after Letterman left NBC and moved to Late Show on CBS. Late Night with Conan O'Brien then filled the time slot. As of March 2, 2009, the slot has been filled by Late Night with Jimmy Fallon. It will be filled by Seth Meyers in the spring of 2014, after Fallon becomes host of The Tonight Show.

The adventures of Freakazoid, a manic, insane superhero who battles with an array of super villains.

Follow a younger Patrick Star living at home with his family, where he hosts his own variety show for the neighborhood from his television-turned-bedroom.

Jonathan Ross's take on current topics of conversation, guest interviews and live music from both a guest music group and the house band.