An overweight guy's struggles through different stages of his life and how the number 110 doesn't leave him alone at every stage.

Annie Easton is a fat young woman who wants to change her life — but not her body. She struggles to make it as a journalist while juggling bad boyfriends, sick parents, and a perfectionist boss, while the world around her deems her unsatisfactory due to her weight. Then, she realizes that she is just as good as anyone else and acts on it.

Four adults nearing 40, living under the same roof, struggle to keep their relationships and their individual dreams alive.

Lifelong best friends Alexa and Katie are eagerly anticipating the start of their freshman year of high school. The pals confront a crisis that leaves them feeling like outsiders at a time when what seems to matter most is fitting in.

Sheila Rubin is a quietly tormented housewife in ’80s San Diego. Behind closed doors, she battles extreme personal demons and a vicious inner voice. But things change when she discovers aerobics, sparking a journey toward empowerment and success.

The Slaton sisters averaging over a thousand pounds, have always depended on each other for support. Now in their 30s, Amy wants to have children, but cannot due to her weight, while her elder sister Tammy is near bedridden.

A shallow model suddenly dies in an accident only to find her soul resurfacing in the body of a brilliant, plus-sized attorney.

Oscar's life seems almost perfect...sure he's divorced and his apartment is a mess, but he's the host of a well-known sports show, and is enjoying his bachelor lifestyle in New York City. That is until his college friend, Felix, shows up at Oscar's apartment having just been dumped by his wife. Oscar does his best to console his old buddy and get him back on the dating horse, but his attempts uncover just how unresolved his own feelings are about his ex.

Hannah Wells tutors hockey captain Garrett Graham to win over her crush. Their deal becomes real connection as they face their pasts. Friends Logan, Dean, Tucker, and Allie navigate college life and love.

Jim Jefferies, an edgy, foul-mouthed stand-up comedian from Australia, in his mid-30s and living in LA, is endeavoring to make his life and career more “legit,” only to find it a difficult, uncomfortable uphill struggle every step of the way. Jim is encouraged in his quest by Steve, his neurotic best friend and roommate, a cyber-law library salesman who struggles to stay on his feet in the wake of a divorce, and Steve’s brother Billy, who suffers from advanced staged Muscular Dystrophy and is confined to a wheelchair.

A sportscaster becomes a full-time dad when his ex-wife decides to accept a job out of the country and his teenage daughter, Breanna, moves in with him.

A comedy about a working class Chicago couple who find love at an Overeaters Anonymous meeting.

The daily trials and tribulations of handyman Tim Taylor, a TV show host raising three boys with help from his loyal co-host, domineering wife, and unseen neighbor.

The story of Elizabeth Holmes, the enigmatic Stanford dropout who founded medical testing start-up Theranos. Lauded as a Steve Jobs for the next tech generation and once worth billions of dollars, the myth crumbled when it was revealed that none of the tech actually worked, putting thousands of people's health in grave danger.

A widower and aeronautical engineer named Steven Douglas raises three sons with the help of his father-in-law, and later the boys' great-uncle. An adopted son, a stepdaughter, wives, and another generation of sons join the loving family in later seasons.

A motley group of London con artists pull of a series of daring and intricate stings.

Holden wakes up from a coma after 12 years and discovers new abilities that propel him into the middle of a dangerous conspiracy.

A mid-life crisis tale about the unlikely chairman of the English department in a badly underfunded college in the Pennsylvania rust belt.

Desperate times call for desperate measures and Ray Drecker's situation couldn't be much tougher. The former high school sports legend turned middle-aged high school basketball coach is divorced and struggling to provide for his kids when his already run-down house catches fire. Looking to take on a second job, Ray decides to exploit his best asset in a last-ditch attempt to change his fortunes.

As Dwayne Johnson runs for president in 2032, he takes a comedic look back at his extraordinary life through the outrageous stories of his family and youth that shaped him into the man he is today. He explores his childhood years living amid influential wrestling icons while his dad rose to fame in the business, his rebellious teenage years attending high school in Pennsylvania, and his football years teamed up with powerhouse players at the University of Miami. In his telling, Johnson explains that while his experiences have been larger than life, he remains a down-to-earth guy who still relates to the American people.

The daughter of a former Hooter's waitress and an ex-pro wrestler, Margo is a recent college dropout and aspiring writer. Faced with a new baby, mounting pile of bills, and dwindling number of ways to pay them, Margo must find a way forward.