Jamie Pickup

Louis immerses himself in the world of Ohio's state psychiatric hospitals, meeting patients who have committed crimes - at times horrifically violent - while in the grip of severe mental illness.

Following on from his recent look at alcoholism, the UK’s premier documentarian returns with another sensitive film, this time on living with a brain injury. Earl’s personality and interests have radically altered since he was involved in a car crash, while Dan – who sustained his injury in the late 90s – is desperate to live independently again. Elsewhere, Amanda is struggling to readjust to family life, and Natalie’s carers share her especially affecting story.

Sixteen years after his documentary When Louis Met Jimmy, Theroux seeks to understand how he was tricked by a man who became his friend.

The programme follows Theroux as he travels to the United States to meet people who own animals normally found in Africa and Asia, including big cats and dangerous primates. In the programme, Theroux visits GW Exotic Animal Foundation in Oklahoma.

Louis is at Cedars Sinai Medical Centre in L.A to learn about the American way of death.