In the present, artist Tom Warshaw recalls his traumatic coming of age. As a 13-year-old growing up in New York City in 1973, Tom hangs out with Pappass, a mentally disabled man. With Tom's mother battling depression after the death of her husband, the young boy is left to his own devices. When Tom develops a crush on schoolmate Melissa, Pappass feels abandoned and begins behaving erratically.

The story of Bea Johnson from birth to graduation as she navigates life with an intellectually disabled parent and an extended family who can't quite agree on the best way to help.

After writing a soon-to-be bestselling novel, writer and committed bachelor Harper attempts to hide the fact that his saucy new book is loosely based on the lives and loves of his tight-knit group of friends. Harper is set to be best man at his friend Lance's wedding, and all his friends will be in attendance. When an advance copy of the book makes its way into the hands of his ex-flame, Jordan, Harper attempts to keep it under wraps.

A man in his mid-20s, still living at home with his mother and stepfather, puts all his eggs in one basket: the girl who works at his local coffee shop. The problem is, she has a serious boyfriend. As they become closer, the line between friendship and intimacy is blurred, and the situation forces both to examine where they are in their lives.

A young girl tries to fit in with a clique of popular middle school girls after moving into the guest house of one of their homes.

When a son and mother move to Seattle in hopes for a better life, the mother meets a seemingly polite man. Things go south when the man turns out to be abusive, endangering their lives. As the mother struggles to maintain hope in an impossible situation, the son has plans to escape.

Writer Harry Block draws inspiration from people he knows, and from events that happened to him, sometimes causing these people to become alienated from him as a result.

A struggling young writer finds his life and work dominated by his unfaithful wife and his radical feminist mother, whose best-selling manifesto turns her into a cultural icon.

Restless and unhappy, two couples get caught up in infidelity and deception. Barry is a sullen businessman married to Mary, a writer who is unsatisfied with their relationship. Mary begins an affair with Jerry, a smug theater professor and husband of her friend, Terri, who is also a writer. Adding to the adulterous mix are Cary, a callous doctor, and Cheri, an art-gallery assistant.

A petty criminal fakes insanity to serve his sentence in a mental ward rather than prison. He soon finds himself as a leader to the other patients—and an enemy to the cruel, domineering nurse who runs the ward.

Movie star Roxy Carmichael is abandoning the bright lights of Hollywood, Calif. and returning to her small Ohio hometown -- at least long enough to dedicate a city building. And now the whole town of Clyde is bracing for Carmichael's return, most of all her now-married old flame Denton Webb and troubled teen Dinky Bossetti. An orphan with few friends, Dinky is convinced that Carmichael is her birth mother, and that the actress will reclaim her when she returns.

Teenagers Solomon and Tummler kill time in Xenia, Ohio, a small town that has never recovered from the tornado that ravaged the community in the 1970s.

Middle-aged and divorced, Wilson finds himself lonely, smug, and obsessed with his past.

John Bennett, a man whose childhood wish of bringing his teddy bear to life came true, now must decide between keeping the relationship with the bear or his girlfriend, Lori.

After returning to Los Angeles from a group therapy session, documentary filmmaker Bob Sanders and his wife, Carol, find themselves becoming vigilante couples counselors, offering unsolicited advice to their best friends, Ted and Alice Henderson. Not wanting to be rude, the Hendersons play along, but some latent sexual tension among the four soon comes bubbling to the surface, and long-buried desires don't stay buried for long.

Famous and wealthy funnyman George Simmons doesn't give much thought to how he treats people until a doctor delivers stunning health news, forcing George to reevaluate his priorities with a little help from aspiring stand-up comic Ira.

Jeffrey Dahmer struggles with a difficult family life as a young boy. During his teenage years he slowly transforms, edging closer to the serial killer he was to become.

Calvin Campbell is a former professional baseball player sent to an early retirement due to his panic attacks at the plate. Even though he had all the talent for the big leagues, he struggles with the curveballs life has thrown him. Today, he mindlessly sleepwalks through his days and the challenge of raising his teenager daughter. His life is in a slow downward spiral when it is suddenly awakened and invigorated by the most unlikely person – Produce, a young-man with Down syndrome who works at the local grocery store.

In trouble with the local authorities, Mabel Simmons, notoriously known as Madea, is on the run from the law. With no place to turn, she moves in with her friend Bam who is recovering from surgery. Unbeknownst to Bam however, Madea is only using the "concerned friend" gag as a way to hide out from the police.

Stephanie, a dedicated mother and popular vlogger, befriends Emily, a mysterious upper-class woman whose son Nicky attends the same school as Miles, Stephanie's son. When Emily asks her to pick Nicky up from school and then disappears, Stephanie undertakes an investigation that will dive deep into Emily's cloudy past.