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Alice Howland, happily married with three grown children, is a renowned linguistics professor who starts to forget words. When she receives a devastating diagnosis, Alice and her family find their bonds tested.

Four siblings' lives change drastically when their ailing mother takes a turn for the worse over the holiday season.

When lapsed Jew and former cardiologist Harry suddenly decides to spend his retirement as a pig farmer in Nazareth, Israel, the move deeply shocks his family and his new neighbours. Back in New York, Harry’s ex-wife Monica is trying to manage the lives of their adult children, Annabelle and David, as well as her own.

A terminally ill mother invites her family to their country house for one final gathering, but tensions quickly boil over between her two daughters.

Thomas Montgomery, a married father of two young daughters, gets seduced by the world of online gambling and chat rooms where a virtual romance and sexual obsession ultimately leads to the murder of an innocent man.

In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.

A man refuses all assistance from his daughter as he ages and, as he tries to make sense of his changing circumstances, he begins to doubt his loved ones, his own mind and even the fabric of his reality.

A poor, struggling South Carolinian mother and daughter face painful choices with their resolve and pride. Bone, the eldest daughter, and Anney her tired mother, grow both closer and farther apart: Anney sees Glen as her last chance.

When seventeen-year-old Hannah stumbles upon a website about Thinspiration--an online community devoted to anorexia as a life choice--she becomes an obsessive follower of the site founder, ButterflyAna. By the time Hannah's family realizes what is happening and get Hannah the help she needs, the disease has fully taken hold and Hannah is refusing to eat. Will this family be able to exorcise the demon of anorexia from their lives?

A troubled young woman becomes obsessed with her mysterious new neighbor, who bears a striking resemblance to the girl's dead mother.

In the town of Martin, Tennessee, Chip Hines, a precocious six year old, has only known life with his two dads, Cody and Joey. And a good life it is. When Cody dies suddenly in a car accident, Joey and Chip struggle to find their footing again. Just as they begin to, Cody's will reveals that he named his sister as Chip's guardian. The years of Joey's acceptance into the family unravel as Chip is taken away from him. In his now solitary home life, Joey searches for a solution. The law is not on his side, but friends are. Armed with their comfort and inspired by memories of Cody, Joey finds a path to peace with the family and closer to his son.

94-year-old Eleanor Morgenstein tries to rebuild her life after the death of her best friend. As a result, she moves back to New York City after living in Florida for decades.

After a heartbreaking loss, a grandfather struggling to reclaim his passion for painting finds the inspiration to create again.

Calvin Campbell is a former professional baseball player sent to an early retirement due to his panic attacks at the plate. Even though he had all the talent for the big leagues, he struggles with the curveballs life has thrown him. Today, he mindlessly sleepwalks through his days and the challenge of raising his teenager daughter. His life is in a slow downward spiral when it is suddenly awakened and invigorated by the most unlikely person – Produce, a young-man with Down syndrome who works at the local grocery store.

Years after her son's suicide, a woman longs to confront both the past and a friend of his who took his business idea.

A Midwestern husband and father announces his plan to have a sex change operation.

A young man with a bright future suffers a near-fatal accident and recreates his new life with the help of an unlikely animal friend.

When an accomplished pianist is diagnosed with the devastating and incurable disease ALS, she hires a directionless young woman who becomes her full-time caregiver. Complete opposites, the strangers form a life-changing bond inspiring each other to live life to fullest, while being brought together by the most challenging of circumstances.

The story of a New York pro baseball team and two of its players. Henry Wiggen is the star pitcher and Bruce Pearson is the normal, everyday catcher who is far from the star player on the team and friend to all of his teammates. During the off-season, Bruce learns that he is terminally ill, and Henry, his only true friend, is determined to be the one person there for him during his last season with the club. Throughout the course of the season, Henry and his teammates attempt to deal with Bruce's impending illness, all the while attempting to make his last year a memorable one.

A woman wakes up in the middle of the night on board a train, but she can't remember how she got there. Danger and suspense ensue.