Grindhouse combines Robert Rodriguez's Planet Terror, a horror comedy about a group of survivors who battle zombie-like creatures, and Quentin Tarantino's Death Proof, an action thriller about a murderous stuntman who kills young women with modified vehicles. It is presented as a double feature with fictitious exploitation trailers preceding each segment.

With his partner Caprice, celebrity performance artist Saul Tenser publicly showcases the metamorphosis of his organs in avant-garde performances. An investigator from the National Organ Registry obsessively tracks their movements, which is when a mysterious group is revealed... Their mission — to use Tenser's notoriety to shed light on the next phase of human evolution.

Looking for work, Aaron comes across a cryptic online ad: “$1,000 for the day. Filming service. Discretion is appreciated.” Low on cash and full of naiveté, he decides to go for it. He drives to a cabin in a remote mountain town where he meets Josef, his cinematic subject for the day. Josef is sincere and the project seems heartfelt, so Aaron begins to film. But as the day goes on, it becomes clear that Josef is not who he says, and his intentions are not at all pure.

An English pianist living in Rome witnesses the brutal murder of his psychic neighbor. With the help of a tenacious young reporter, he tries to discover the killer using very unconventional methods. The two are soon drawn into a shocking web of dementia and violence.

As a serial killer stalks the city, Julia — a young actress who just moved to town with her husband — notices a mysterious stranger watching her from across the street.

An elderly heiress is killed by her husband who wants control of her fortunes. What ensues is an all-out murder spree as relatives and friends attempt to reduce the inheritance playing field, complicated by some teenagers who decide to camp out in a dilapidated building on the estate.

Detectives Jake Doyle and Mary Kelly seek the help of an incarcerated serial killer named The Artist when a copycat killer strikes. While Mary searches for clues in The Artist's brilliant but twisted psyche, she and Jake are lured into a diabolical game of cat and mouse, racing against time to stay one step ahead of The Artist and his copycat.

A young opera singer is stalked by a deranged fan bent on killing the people associated with her to claim her for himself.

Isabella, a young model, is murdered by a mysterious masked figure at a fashion house in Rome. When her diary, which details the house employees' many vices, disappears, the masked killer begins killing off all the models in and around the house to find it.

A teenager is stuck in a time loop that is not quite the same each time. She must uncover the truth but her actions have consequences for herself and others.

In town for a job interview, a young woman arrives at her Airbnb late at night only to find that it has been mistakenly double-booked and a strange man is already staying there. Against her better judgement, she decides to stay the night anyway.

As he helps a young artist with her upcoming exhibition, the owner of a mannequin shop's deadly, suppressed desires come to the surface.

After a young, middle-class couple moves into what seems like a typical suburban house, they become increasingly disturbed by a presence that may or may not be demonic, but is certainly the most active in the middle of the night.

Detectives are thrust into a chilling hunt for a sadistic serial killer from the past whose return marks the beginning of a new wave of grotesque, otherworldly crimes tied to a cosmic force.

A group of young horror fans go searching for a film that mysteriously vanished years ago but instead find that the demented killer from the movie is real, and he's thrilled to meet fans who will die gruesomely for his art.

When the Smurl family moves into a duplex, they find out it's haunted. When the Catholic Church is no help, they reach out to famous demonologists Ed and Lorraine Warren

A strange doorway appears in the basement of a furniture showroom.

Wisecracking reporter Carl Kolchak investigates a string of murders in Las Vegas and suspects the culprit is a vampire. His editor thinks he's crazy and the police think he's a nuisance, so Kolchak takes matters into his own hands.

In Los Angeles, on Halloween night, a hitman tries to transport a corpse in plain sight, but people he stumbles upon on the street, believing that his sophisticated appearance is a magnificent disguise, constantly stand in his way to congratulate him.

A masked serial killer with psychosexual issues strangles female coeds with scarves before dismembering them. When a wealthy student identifies one of the scarves and thinks she has a lead on a suspect, she becomes the killer's next target, retreating to her family's remote cliffside villa with three of her girlfriends.