Charles Dexter Ward, a wealthy scientist, uses an ancient diary and human remains to begin a terrifying and bloody pursuit for immortality.

A young medical student struggling to pay tuition is drawn into the shady world of underground body-modification.

The film contains five stories set on desolate stretches of a desert highway. Two men on the run from their past, a band on its way to a gig, a man struggling to get home, a brother in search of his long-lost sister and a family on vacation are forced to confront their worst fears and darkest secrets in these interwoven tales.

The infinite playground of forbidden worlds and dangerous lifeforms offered by the sci-fi horror genre will lead to the biggest, maddest, bloodiest V/H/S ever.

When researchers rescue a fellow scientist who survived a meteorite strike in the Arctic, they discover she may not be who they think she is. Is she some-how changed?

Jack Caine is a Houston vice cop who's forgotten the rule book. His self-appointed mission is to stop the drugs trade and the number one supplier Victor Manning. While involved in an undercover operation to entrap Victor Manning, his partner is killed, and a sinister newcomer enters the scene...

A journey into uncharted and forbidden territory through three tales tangled in space and time.

Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.

Vice detective Bob Hightower finds his ex-wife murdered and daughter kidnapped by a cult. Frustrated by the botched official investigations, he quits the force and infiltrates the cult to hunt down the leader with the help of the cult’s only female victim escapee, Case Hardin.

A woman returns to her family home and discovers it to be inhabited by monsters.

In town for a job interview, a young woman arrives at her Airbnb late at night only to find that it has been mistakenly double-booked and a strange man is already staying there. Against her better judgement, she decides to stay the night anyway.

Broke, and in desperate need to update her portfolio, New York City model Katie calls a number from a tear-off flyer offering free photos. But this innocent attempt quickly turns into an unthinkable kidnapping nightmare where she's ripped away from everyone and everything she knows.

The archangel Gabriel returns to try to destroy the human race he despises so much, with the help of a suicidal teen and the opposition of the angel Danyael.

A beautiful woman from the city, Jennifer Hills, rents an isolated cabin in the country to write her latest novel. Soon, a group of local lowlifes subject her to a nightmare of degradation, rape, and violence.

Two doctors find their graveyard shift inundated with townspeople ravaged by sores. Among the wounded is Cherry Darling, a dancer whose leg was ripped from her body. As the invalids quickly become enraged aggressors, Cherry and her ex-boyfriend El Wray lead a team of accidental warriors into the night.

Two women—Diana, a flamboyant and ruthless thief, and Evie, a seemingly innocent young woman with a troubled past—become embroiled in a series of horrific murders on the island of Malta.

While staying at an isolated island resort, James and Em are enjoying a perfect vacation of pristine beaches, exceptional staff, and soaking up the sun. But guided by the seductive and mysterious Gabi, they venture outside the resort grounds and find themselves in a culture filled with violence, hedonism, and untold horror. A tragic accident leaves them facing a zero tolerance policy for crime: either you'll be executed, or, if you’re rich enough to afford it, you can watch yourself die instead.

A wisecracking New York reporter intrudes on a research scientist's quest to unmask The Moon Killer.

In the last days of 1999, ex-cop turned street hustler Lenny Nero receives a disc which contains the memories of the murder of a prostitute. With the help of bodyguard Mace, he starts to investigate and is pulled deeper and deeper in a whirl of murder, blackmail and intrigue.

Years after a mysterious plague has devastated the planet and turned most of humanity into blood-hungry creatures, a rogue drifter on a vengeful hunt stumbles across a band of survivors in an abandoned police station and reluctantly agrees to try to help them defend themselves and escape to the sanctuary they so desperately need.