Heading east to Fort Worth to hire a schoolteacher for his frontier town home, Link Jones is stranded with singer Billie Ellis and gambler Sam Beasley when their train is held up. For shelter, Jones leads them to his nearby former home, where he was brought up an outlaw. Finding the gang still living in the shack, Jones pretends to be ready to return to a life crime.
Jake Wade breaks Clint Hollister out of jail to pay off an old debt, though it's clear there is some pretty deep hostility between them. They part, and Jake returns to his small-town marshal's job and his fiancée only to find he has been tracked there by Hollister. It seems they were once in a gang together and Jake knows where the proceeds of a bank hold-up are hidden. Hollister and his sidekicks make off into the hills, taking along the trussed-up marshal and his kidnapped bride-to-be to force the lawman to show them where the loot is.
Three outlaws come to the aid of a young girl after her father is killed.
When hired killer John Gant rides into Lordsburg, the town's folk become paranoid as each leading citizen has enemies capable of using the services of a professional killer for personal revenge.
Three teenage farm boys stumble upon Harry Spikes, a local bandit wounded in a gun battle. While Harry is recuperating, he regales the young men with stories of his exciting past. The adventurous tales inspire them to start a gang of their own. Failing at their first attempt to rob a bank, the boys convince the gruff Spikes to teach them the ways of the desperado.
Two tough Kentucky mountaineers join a trading expedition from St. Louis up the Missouri River to trade whisky for furs with the Blackfoot Indians. They soon discover that there is much more than the elements to contend with.
An oppressed Mexican peasant village hires seven gunfighters to help defend their homes.
An ex-con seeks revenge on the man who put him in prison by planning a robbery of the latter's stagecoach, which is transporting gold. He enlists the help of a partner, who could be working for his nemesis.
Texas Ranger Jake Cutter arrests gambler Paul Regret, but soon finds himself teamed with his prisoner in an undercover effort to defeat a band of renegade arms merchants and thieves known as Comancheros.
Notorious shootist and womanizer Quirt Evans' horse collapses as he passes a Quaker family's home. Quirt has been wounded, and the kindly family takes him in to nurse him back to health against the advice of others. The handsome Evans quickly attracts the affections of their beautiful daughter, Penelope. He develops an affection for the family and their faith, but his troubled past follows him.
A gunhand named Lane is hired by a widow, Mrs. Lowe, to find gold stolen by her deceased husband so that she may return it and clear the family name.
A crooked politician finds himself being accused of murder by a gangster from whom he refused help during a re-election campaign.
Texas Ranger Dusty Rivers ("Isn't that a contradiction in terms?", another character asks him) travels to Canada in the 1880s in search of Jacques Corbeau, who is wanted for murder. He wanders into the midst of the Riel Rebellion, in which Métis (people of French and Native heritage) and Natives want a separate nation. Dusty falls for nurse April Logan, who is also loved by Mountie Jim Brett. April's brother is involved with Courbeau's daughter Louvette, which leads to trouble during the battles between the rebels and the Mounties. Through it all Dusty is determined to bring Corbeau back to Texas (and April, too, if he can manage it.)
Pursued by the big-time gambler he robbed, John Muller assumes a new identity—with unfortunate results.
Lucky Prescott's life is changed forever when she moves from her home in the city to a small frontier town and befriends a wild mustang named Spirit.
An ex-fireman with PTSD goes on the run when accused of a crime he doesn't even remember committing, leading him down a rabbit hole of conspiracy to the highest degree.
Davy Crockett and his sidekick Georgie compete against boastful Mike Fink ("King of the River") in a boat race to New Orleans. Later, Davy and Georgie, allied with Fink, battle a group of river pirates trying to pass themselves off as Native Americans.
Drifter Cole Harden is accused of stealing a horse and faces hanging by self-appointed Judge Roy Bean, but Harden manages to talk his way out of it by claiming to be a friend of stage star Lillie Langtry, with whom the judge is obsessed, even though he has never met her. Tensions rise when Harden comes to the defense of a group of struggling homesteaders who Judge Bean is trying to drive away.
Posing as hunters, a group of terrorists are in search of $100 million that was stolen and lost in a plane crash en route from Afghanistan.
Questions arise when Senator Stoddard attends the funeral of a local man named Tom Doniphon in a small Western town. Flashing back, we learn Doniphon saved Stoddard, then a lawyer, when he was roughed up by a crew of outlaws terrorizing the town, led by Liberty Valance. As the territory's safety hung in the balance, Doniphon and Stoddard, two of the only people standing up to him, proved to be very important, but different, foes to Valance.
