Midnight Examination Room 5: Target the Nurse!

The candid sexual experiences of three close friends working as nurses, unfolding night after night!

Race queen Minami has been hospitalized. Rinko is consumed by jealousy as Minami tries to seduce Dr. Makoto.

Rinko and her friends go to a group date at Kei's invitation, but are disappointed to find themselves surrounded by a group of unattractive men who don't seem likely to be popular with women. However, Michiyo is attracted to Iwabuchi, one of the men, and ends up going to a hotel with him. Afterwards, Rinko and her friends receive an invitation to another group date, this time to a cosplay one.

Nurse Rinko works at a hospital where intern Yoshioka joins the staff. Rinko falls in love with Yoshioka at first sight. Yoshioka becomes captivated by Ayakoji Mika, a dominatrix among the hospitalized patients. Rinko witnesses Mika engaging in sexual activity in the examination room late at night. Who is Mika's partner?

Rinko still has feelings for Dr. Yoshioka, but there is no progress whatsoever. Her colleague Michiyo tells her to "make up your mind!", but the indecisive Rinko can't bring herself to confess. Hearing this, Megumi suggests they sneak into Yoshioka's house. The three of them, dressed as female ninjas, break into Yoshioka's house, but the hospital's head nurse, Ibuki, is there...