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After witnessing a bizarre, traumatic incident involving a patient, Dr. Rose Cotter starts experiencing frightening occurrences that she can't explain.

Jigsaw has disappeared. Along with his new apprentice Amanda, the puppet-master behind the cruel, intricate games that have terrified a community and baffled police has once again eluded capture and vanished. While city detectives scramble to locate him, Doctor Lynn Denlon and Jeff Reinhart are unaware that they are about to become the latest pawns on his vicious chessboard.

A young medical student struggling to pay tuition is drawn into the shady world of underground body-modification.

Dr Simon Helder, sentenced to an insane asylum for crimes against humanity, recognises its director as the brilliant Baron Frankenstein, the man whose work he had been trying to emulate before his imprisonment. Frankenstein utilises Helder's medical knowledge for a project he has been working on for some time. He is assembling a man from vital organs extracted from various inmates in the asylum. And the Baron will resort to murder to acquire the perfect specimens for his most ambitious project ever.

An extremely wealthy elderly man dying from cancer undergoes a radical medical procedure that transfers his consciousness to the body of a healthy young man but everything may not be as good as it seems when he starts to uncover the mystery of the body's origins and the secret organization that will kill to keep its secrets.

Pauline, a disturbed, outcast teenager, has a fascination with surgery and experiences violent, psychosexual fantasies, all while aspiring to a career in medicine.

An insecure Chinese-American teenager undergoes experimental surgery to appear white, hoping to secure the prom queen title and peer acceptance.

Conducting clandestine experiments within the morgue at Miskatonic University, scientist Herbert West reveals to a fellow graduate student his groundbreaking work concerning the re-animation of fresh corpses.

Five medical students experiment with "near death" experiences, until the dark consequences of past tragedies begin to jeopardize their lives.

With his partner Caprice, celebrity performance artist Saul Tenser publicly showcases the metamorphosis of his organs in avant-garde performances. An investigator from the National Organ Registry obsessively tracks their movements, which is when a mysterious group is revealed... Their mission — to use Tenser's notoriety to shed light on the next phase of human evolution.

Unperturbed by the disastrous outcome of his previous meddling with the dead, Dr. West continues his research into the phenomenon of re-animation; only this time, he plans to create life – starting with the heart of his young protégé Dan's dearly deceased Meg Halsey.

Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.

As a deadly battle rages over Jigsaw's brutal legacy, a group of Jigsaw survivors gathers to seek the support of self-help guru and fellow survivor Bobby Dagen, a man whose own dark secrets unleash a new wave of terror.

When a group of friends discover how to conjure spirits using an embalmed hand, they become hooked on the new thrill, until one of them goes too far and unleashes terrifying supernatural forces.

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Chris and his girlfriend Rose go upstate to visit her parents for the weekend. At first, Chris reads the family's overly accommodating behavior as nervous attempts to deal with their daughter's interracial relationship, but as the weekend progresses, a series of increasingly disturbing discoveries lead him to a truth that he never could have imagined.

In a massive, mysterious chamber, fifty strangers awaken to find themselves trapped with no memory of how they got there. Organized in an inward-facing circle and unable to move, they quickly learn that every two minutes, one of them must die…executed by a strange device in the center of the room.

Eccentric scientist Victor Von Frankenstein creates a grotesque creature in an unorthodox scientific experiment.

Following the sudden death of his mother, a mild-mannered but anxiety-ridden man confronts his darkest fears as he embarks on an epic odyssey back home.

A series of down-on-their-luck individuals enter the decrepit and spine-chilling Rialto theater, only to have their deepest and darkest fears brought to life on the silver screen by The Projectionist – a mysterious, ghostly figure who holds the nightmarish futures of all who attend his screenings.