Amanda's deathbed request to her son, John, was for him to destroy all the lab notes etc. from her last experiment. She also blurts out he had a brother. At the funeral John meets Melissa, who claims to be his mother's biggest fan. Together with some of John's friends they go to Amanda's house, but none are prepared for what they find there.
Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.
When brilliant, eccentric scientist Seth Brundle makes a huge technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and the two become one.
Mad scientist turns a man into an electrically-controlled monster to do his bidding.
Researchers on the undersea lab Aquatica have genetically altered the brains of captive sharks to develop a cure for Alzheimer's disease. But there's an unexpected side effect: the sharks got smarter, faster, and more dangerous. After a big storm damages their remote research facility, they must fight for their lives.
The Resonator, a powerful machine that can control the sixth sense, has killed its creator and sent his associate into an insane asylum. When a psychiatrist becomes determined to continue the experiment, she unwittingly opens the door to a hostile parallel universe.
A scientist trains a man with an advanced telepathic ability called 'scanning' to stop a dangerous Scanner with extraordinary psychic powers from waging war against non-Scanners.
Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.
After losing his wife and his memory in a car accident, a single father undergoes an experimental treatment that causes him to question who he really is.
A masked maniac terrorizes the same small community where a murderer known as the Phantom Killer struck decades earlier.
When their plans for a nature trip go awry, Polly and boyfriend Seth decide to check into a motel. On their way, they're carjacked and kidnapped by low-rent crooks Dennis and Lacey, who take the victims and their SUV to a nearby gas station. Along the way, they encounter an increasingly terrifying horde of parasites, and if any of them intend to survive, they'll have to outsmart the deadly organisms.
Dr. Peyton Westlake is on the verge of realizing a major breakthrough in synthetic skin when his laboratory is destroyed by gangsters. Having been burned beyond recognition and forever altered by an experimental medical procedure, Westlake becomes known as Darkman, assuming alternate identities in his quest for revenge and a new life with a former love.
A wisecracking New York reporter intrudes on a research scientist's quest to unmask The Moon Killer.
Young Macy is abducted by a deranged, monstrous figure who wants to raise her as its child.
In medieval England, Anne and her domineering mother-in-law Morwen struggle to survive on the outskirts of society. But when a man from Anne's past returns from war, a curse begins to take shape through a mysterious knight and threatens to destroy them all.
On a trip to Colombia, a group of college students encounter a fifty-foot boa constrictor, hungry for blood.
Five young mutants, just discovering their abilities while held in a secret facility against their will, fight to escape their past sins and save themselves.
A Victorian scientist returns to London with his paleontological bag-of-bones discovery from Papua New Guinea. Unfortunately, when exposed to water, flesh returns to the bones, unleashing a malevolent entity on the scientist's family and friends.
First-time father Henry Spencer tries to survive his industrial environment, his angry girlfriend, and the unbearable screams of his newly born mutant child.
A research scientist explores the boundaries and frontiers of human consciousness. Using sensory deprivation and hallucinogenic mixtures from Native American shamans, he explores these altered states of cognizance and finds that memory, time, and reality itself are states of mind.